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How Is ELREXFIO Given?

What to expect when starting ELREXFIO

ELREXFIO is a ready-to-use treatment

ELREXFIO will be given to you by your healthcare provider as an injection under your skin (subcutaneous injection), usually in your stomach area (abdomen). Your thigh or another area of your body may also be used.

1

“Step-up” dosing schedule

During your first week of treatment, you will begin with 2 “step-up” doses of ELREXFIO. Building up to a full dose will help your body’s immune system adjust to ELREXFIO. You should be hospitalized while receiving these first 2 doses due to the risk of cytokine release syndrome (CRS). Your first treatment dose will be your third dose, which is usually given on day 8 of treatment.

2

Weekly dosing

After completing the "step-up" dosing schedule, you will likely begin weekly treatment with ELREXFIO at your healthcare provider’s office or another outpatient setting.

3

Every other week dosing

After 6 months of treatment, your healthcare provider will evaluate your progress and decide if an every other week dosing schedule could be right for you.

Typical ELREXFIO dosing schedule

ELREXFIO (elranatamab-bcmm) dosing schedule chart

ELREXFIO (elranatamab-bcmm) dosing schedule chart mobile

  • Before your first 3 doses of ELREXFIO, your healthcare provider will give you other premedication to help reduce your risk of CRS, a serious side effect
  • Your healthcare provider will monitor you for symptoms of CRS and neurologic problems
  • After 6 months of treatment, your healthcare provider will evaluate your progress and decide if an every other week dosing schedule could be right for you

After 6 months of treatment, ELREXFIO offers every other week dosing for patients who have achieved a partial response or better

Getting Started With ELREXFIO

This free guide will help you prepare for ELREXFIO treatment and provide you with a tool to easily track how you’re feeling after receiving each dose.

Download now

Getting Started with ELREXFIO (elranatamab-bcmm) Guide
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